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Steven Lewis L. Neurological Disorders due to Systemic Disease


How do you identify which neurological syndromes occur due to systemic disease? Neurological problems commonly occur in the context of underlying systemic disease, and may even be the presenting symptom of a medical condition that has not yet been diagnosed. Consequently neurologists need to be aware when a neurological presentation might indicate an underlying systemic disorder. Neurologic Disorders due to Systemic Disease provides the tools you need to make these connections. The unique Neurologic presentations-based approach relates to the common clinical situations you encounter, including: Headache Stroke Movement disorders Neuromuscular disorders Encephalopathies, Seizures, Myelopathies, Neuro-Ophthalmologic and Neuro-otologic disorders, Sleep disorders, and others Major categories of systemic illness are explored for each presentation to guide you towards a likely cause. These include: Endocrine, electrolyte, and metabolic disorders Systemic autoimmune disorders Organ dysfunction and failure, and critical medical illness Systemic cancer and paraneoplastic disorders Systemic infectious disease Complications due to drugs and alcohol Vitamin and mineral deficiencies Written by a leading cast of experts, with a practical approach including ‘things to remember’ for each presentation, Neurologic Disorders due to Systemic Disease should be on every neurologist’s desk.

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Christopher Shaw A. Neural Dynamics of Neurological Disease


The emerging understanding of age-related neurological disorders suggests that notions of a single causal gene/toxin being responsible is likely incorrect. Neurological disorders probably arise due to a unique intersection of multiple genetic and toxic factors, combined with additional contributions of age, stage of development, immune system actions, and more. This perspective leads to the view that rather than reflecting only one pathway to end-state disease, each is a spectrum disorder, and every individual case is therefore unique. Neural Dynamics of Neurological Disease argues for a fundamental rethinking of what we think we know about neurological disorders, how they arise and progress, and, crucially, what might be done to «cure» them. It first introduces the concept of neural dynamics of neurological disease, then examines various diseases and gives examples of the interplay of elements such as neural systems, cell types, and biochemical pathways that can contribute to disease. The concluding chapters point the way to how the emerging notion of neurological disease as a dynamic process may lead to more successful treatment options. Providing a cross-disciplinary approach to understanding the origin and progression of neurological disease, Neural Dynamics of Neurological Disease is a timely and valuable resource for neuroscientists, researchers, and clinicians.

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Tahira Farooqui Metabolic Syndrome and Neurological Disorders


Metabolic Syndrome and Neurological Disorders brings together information on the cluster of common pathologies which cause metabolic syndrome – abdominal obesity linked to an excess of visceral fat, insulin resistance, dyslipidemia and hypertension – to provide a comprehensive and cutting edge exploration of the link between metabolic syndrome and neurological disorders. Metabolic syndrome is recognized to play a role in neurological disorders such as stroke, Alzheimers disease, and depression. For the first time in book form, Metabolic Syndrome and Neurological Disorders covers the molecular mechanisms thought to underlie this mirror relationship, as well as how lifestyle and other factors such as oxidative stress and inflammation may play a role in the disease. Grounded in a series of epidemiological studies of metabolic-cognitive syndrome, this book will be a valuable reference for researchers, dietitians, nutritionists, and physicians.

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Paul Reading Sleep Disorders in Neurology. A Practical Approach


The acclaimed guide to quickly and confidently diagnosing and treating sleep disorders in neurological disease—now with more algorithms and tables The diagnosis and treatment of sleep disorders can be extremely challenging for physicians, especially when there is underlying neurological disease. In addition to the primary sleep disorders, there is a growing clinical interest in sleep disturbances associated with common neurological disorders such as Parkinsons disease. This updated and expanded edition of the critically acclaimed Sleep Disorders in Neurology: A Practical Approach provides doctors with expert recommendations and clear guidance on identifying sleep disorders in patients suffering from neurological diseases and providing effective treatment plans. In creating this Second Edition doctors Overeem and Reading made every effort to further enhance the practical approach of the first edition by adding additional algorithms and tables to assist physicians in more rapid decision making. In addition, they expanded the content to include greater coverage of primary sleep disorders. Classification and diagnosis chapters have been revamped to follow the 3rd International Classification of Sleep Disorders. Offers physicians, with a practical approach to diagnosing and treating complex sleep disorders Draws on the expertise of neurologists who specialize in the disorders under discussion Features quick-access algorithms that help physicians rapidly diagnose and treat primary and secondary sleep disorders with confidence Provides guidance on when to consult a sleep specialist in managing a particular sleep disorder and Written by a multinational author team who provide a wider perspective and range of clinical experience Sleep Disorders in Neurology: A Practical Approach, Second Edition is an essential resource for sleep medicine specialists, as well as clinicians and health care professionals not specifically trained in sleep medicine, but who nevertheless need to manage neurologically damaged patients with increasingly recognized sleep/wake disturbances.

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Michael Brainin European Handbook of Neurological Management


Evidence-based, peer reviewed, best practice management guidelines for neurologists Diagnosis is only part of the puzzle. Effective treatment is what your patients really want. The European Federation of Neurological Societies has been publishing management guidelines in the European Journal of Neurology for many years. Developed by a consensus approach, using graded evidence, and then fully peer reviewed, these guidelines provide gold-standard, best-practice guidance to the treatment of neurological disorders. They help bridge the gap between what is done and what should be done for patients with neurological disorders. The basic guidelines have been expanded with Recommendations based on strong evidence and Good Practice Points where only weaker evidence is available. The Guidelines in this volume include, amongst others: Neurostimulation therapy for neuropathic pain Molecular diagnosis for a range of neurological conditions Intravenous immunoglobulin in the treatment of neurological diseases Sleep disorders in neurodegenerative disorders and stroke Management of low-grade gliomas Treatment of miscellaneous idiopathic headache disorders The European Handbook of Neurological Management provides a thoroughly rounded and grounded approach to best-practice neurological management using evidence-based principles. Titles of related interest Cerebrovascular Ultrasound in Stroke Prevention, 2e Alexandrov (ed); ISBN 9781405195768 Parkinsonss Disease: Non-Motor and Non-Dopaminergic Features Olanow, Stocchi and Lang (eds); ISBN 9781405191852 Hyperkinetic Movement Disorders: Differential Diagnosis and Treatment Albanese and Jankovic (eds); ISBN 9781444333527

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Tahira Farooqui Neuroprotective Effects of Phytochemicals in Neurological Disorders


Phytochemicals are naturally occurring bioactive compounds found in edible fruits, plants, vegetables, and herbs. Unlike vitamins and minerals, phytochemicals are not needed for the maintenance of cell viability, but they play a vital role in protecting neural cells from inflammation and oxidative stress associated with normal aging and acute and chronic age-related brain diseases. Neuroprotective Effects of Phytochemicals in Neurological Disorders explores the advances in our understanding of the potential neuroprotective benefits that these naturally occurring chemicals contain. Neuroprotective Effects of Phytochemicals in Neurological Disorders explores the role that a number of plant-based chemical compounds play in a wide variety of neurological disorders. Chapters explore the impact of phytochemicals on neurotraumatic disorders, such as stroke and spinal cord injury, alongside neurodegenerative diseases such as Alzheimers and Parkinsons Disease, as well as neuropsychiatric disorders such as depression and schizophrenia. The chapters and sections of this book provide the reader with a big picture view of this field of research. Neuroprotective Effects of Phytochemicals in Neurological Disorders aims to present readers with a comprehensive and cutting edge look at the effects of phytochemicals on the brain and neurological disorders in a manner useful to researchers, neuroscientists, clinical nutritionists, and physicians.

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Roongroj Bhidayasiri International Neurology


This unique textbook deals with the variations in the causes, presentations and treatment of neurological disease throughout human populations. International Neurology is an indispensable guide to the full range of neurological conditions you will see in your ever-changing patient population. Comprehensive coverage of neurological diseases and disorders with a clinical approach to diagnosis, treatment and management Truly international authorship distils expert knowledge from around the world Succinct, bite-sized, templated chapters allow for rapid clinical referral Further reading recommendations for each chapter guide readers requiring more depth of information Endorsed by the World Federation of Neurology

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Marwan Sabbagh N. Geriatric Neurology


Aging affects neurological function leading to neurological disease As society grows older, so do the neurological problems associated with aging. These can be new neurological deficits due to the aging process itself, or the effect of aging on already existing neurological conditions. Neurologists will spend increasing amounts of time managing patients with age-related neurological complications. Geriatric Neurology brings together the wisdom of world-leading experts. They have crafted a new textbook to define this emerging subspecialty from basic science through clinical assessment and medical management to social aspects of patient care. Geriatric Neurology covers: The aging brain in neurology Assessment of the geriatric neurology patient Neurological conditions in the elderly Therapeutics for the geriatric neurology patient Management issues beyond therapeutics Comprehensive in scope but with practical focus for effective patient care, Geriatric Neurology provides top-of-class guidance for the management of elderly patients with neurological disorders.

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Douglas Kirsch Sleep Medicine in Neurology


Recognize, understand, and manage sleep dysfunction in your patients Sleep disorders can cause neurological problems. Neurological problems can cause sleep disorders. Whatever the cause or effect, neurologists need to be well versed in sleep medicine. This enables effective discussion of sleep problems and improved patient outcomes and satisfaction. Sleep Medicine in Neurology introduces the practicing neurologist to sleep medicine, from examination of the patient to treatment of many sleep disorders. With a focused, practical approach throughout, the expert author team covers: History, examination and sleep testing of the patient Insomnia Excessive daytime sleepiness Narcolepsy Obstructive and central sleep apnea Movement disorders in sleep Parasomnias Sleep disorders in children Clinical in approach, practical in execution, Sleep Medicine in Neurology helps you diagnose and treat your sleep-disordered patients more effectively.

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Shereen Ezzat Pituitary Disorders. Diagnosis and Management


Do you want to be up to date on the latest concepts of diagnosis and treatment of patients suffering from disorders of the pituitary gland? Are you looking for an expert guide to the best clinical management? If so, this is the book for you, providing a full analysis of pituitary disorder management from acromegaly to Addisons Disease; from Cushings Disease to hypopituitarism; from hormone disorders to hormone replacement. Well-illustrated throughout, and with contributions from leading specialists in pituitary disease, inside youll find comprehensive and expert coverage, including: Diagnosing pituitary disease Management options for each disorder Complications that can occur Psychological and psychosocial effects of pituitary disease What outcomes you and your patients can expect over the long term Current research and clinical trials related to pituitary disease Pituitary Disorders: Diagnosis and Management is the perfect clinical tool for physicians and health care providers from many related disciplines, and an essential companion for the best quality management of pituitary patients.

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Tahira Farooqui Diet and Exercise in Cognitive Function Neurological Diseases


Diet and exercise have long been recognized as important components of a healthy lifestyle, as they have a great impact on improving cardiovascular and cerebrovascular functions, lowering the risk of metabolic disorders, and contributing to healthy aging. As a greater proportion of the world’s population is living longer, there has been increased interest in understanding the role of nutrition and exercise in long-term neurological health and cognitive function. Diet and Exercise in Cognitive Function and Neurological Diseases discusses the role and impact that nutrition and activity have on cognitive function and neurological health. The book is divided into two sections. The first section focuses on diet and its impact on neurobiological processes. Chapters focus on the impacts of specific diets, such as the Mediterranean, ketogenic and vegan diets, as well as the role of specific nutrients, fats, fatty acids, and calorie restriction on neurological health and cognitive function. The second section of the book focuses on exercise, and its role in maintaining cognitive function, reducing neuroinflammatory responses, regulating adult neurogenesis, and healthy brain aging. Other chapters look at the impact of exercise in the management of specific neurological disorders such Multiple Sclerosis and Parkinson’s Disease. Diet and Exercise in Cognitive Function and Neurological Diseases is a timely reference on the neurobiological interplay between diet and exercise on long-term brain health and cognitive function.

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Andres Kanner Depression in Neurologic Disorders. Diagnosis and Management


Depression in Neurologic Disorders Diagnosis and Management Edited by Andres M. Kanner, MD, Professor of Neurological Sciences and Psychiatry, Rush Medical College at Rush University, Chicago, IL, USA. Why should neurologists care about depression? It is one of the most frequent psychiatric comorbid conditions of neurologic disorders. Not only does it have a negative impact on the quality of patients, but it is also associated with a worse course of the neurologic disease. Yet, more often than not, neurologists have not been trained to recognize clinical depression in their patients. How should neurologists learn to care for depression? By reading Depression in Neurologic Disorders, the caring neurologist will gain a practical overview of: clinical manifestations of depression in the major neurologic disorders how to use screening instruments in clinical practice the identification of patients with an increased suicidal risk basic principles of the management of depressive disorders by the non-psychiatrist The major neurologic disorders covered in Depression in Neurologic Disorders include: Migraine Stroke Epilepsy Parkinson’s Disease Multiple Sclerosis Huntington’s Disease Dementia Traumatic Brain Injury The practical approach is enhanced with the use of case studies and ‘take-home pearls’ throughout. Depression is a common disorder that all neurologists face in their daily clinical practice. Depression in Neurologic Disorders provides the fundamentals of caring for patients who are suffering beyond their diagnosed neurologic disorder. Titles of Related Interest Adult Epilepsy Gregory Cascino and Joseph Sirven (eds); ISBN 978-0-470-74122-1 Hyperkinetic Movement Disorders: Differential Diagnosis and Treatment Alberto Albanese and Joseph Jankovic (eds); 978-0-470-74122-1 Multiple Sclerosis: Diagnosis and Therapy Howard Weiner and James Stankiewicz; 978-0-470-65463-7

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Vicki Rosen Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism


Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 8th Edition is the comprehensive revision of the field-leading reference on bone and mineral health. The eighth edition has been fully revised by the leading researchers and clinicians in the field to provide concise coverage of the widest possible spectrum of metabolic bone diseases and disorders of mineral metabolism. Chapters look to explain basic biological factors of healthy development and disease states and make it easily translatable to clinical interventions. Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism is the definitive, one-stop reference for anyone working in the field of bone health and disease. Visit the companion site to access supplementary materials including videos, editorial team details, downloadable figures, and more.

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Robert Baran and Dawbers Diseases of the Nails their Management


The Scientific and Clinical Encyclopedia of the Nail The human nail provides a complex structure that supports fine manipulation of objects while protecting the extremities. Diseases of the nail disrupt this function. They can cause pain and discomfort, cause disfigurement and are often unsightly with a profound effect on the sufferers self confidence. Baran & Dawbers Diseases of the Nails and their Management has long been recognized as the pre-eminent authority on nail disease. The 13 chapters encompass the scientific and clinical management of all abnormalities of the nails including: Imaging of the Nail Unit The Nail in Dermatologic Disease The Nail in Systemic Disease Congenital and Hereditary Nail Disorders Cosmetics and Nail adornment Surgery of the Nail New to this edition is a superb guide to differential diagnosis by color, shape and location within the nail unit to provide rapid clinical information on nail disorders. Every chapter has been thoroughly updated to ensure a contemporary approach to the therapeutic and cosmetic management of nail disorders. Whether you are new to the field or an experienced practitioner, Baran & Dawber’s Diseases of the Nails and their Management should be on your bookshelf. Titles of Related Interest Harpers Textbook of Pediatric Dermatology, 3e Irvine, Hoeger, Yan (eds); ISBN 978-1-4051-6169-5 Rooks Textbook of Dermatology, 8e Burns, Breathnach, Cox, Griffiths (eds); ISBN 978-1-4051-7695-8

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Ahmed Moustafa A. Computational Models of Brain and Behavior


A comprehensive Introduction to the world of brain and behavior computational models This book provides a broad collection of articles covering different aspects of computational modeling efforts in psychology and neuroscience. Specifically, it discusses models that span different brain regions (hippocampus, amygdala, basal ganglia, visual cortex), different species (humans, rats, fruit flies), and different modeling methods (neural network, Bayesian, reinforcement learning, data fitting, and Hodgkin-Huxley models, among others). Computational Models of Brain and Behavior is divided into four sections: (a) Models of brain disorders; (b) Neural models of behavioral processes; (c) Models of neural processes, brain regions and neurotransmitters, and (d) Neural modeling approaches. It provides in-depth coverage of models of psychiatric disorders, including depression, posttraumatic stress disorder (PTSD), schizophrenia, and dyslexia; models of neurological disorders, including Alzheimer’s disease, Parkinson’s disease, and epilepsy; early sensory and perceptual processes; models of olfaction; higher/systems level models and low-level models; Pavlovian and instrumental conditioning; linking information theory to neurobiology; and more. Covers computational approximations to intellectual disability in down syndrome Discusses computational models of pharmacological and immunological treatment in Alzheimers disease Examines neural circuit models of serotonergic system (from microcircuits to cognition) Educates on information theory, memory, prediction, and timing in associative learning Computational Models of Brain and Behavior is written for advanced undergraduate, Masters and PhD-level students—as well as researchers involved in computational neuroscience modeling research.

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Hugo Kubinyi In vivo Models for Drug Discovery


This one-stop reference is the first to present the complete picture – covering all relevant organisms, from single cells to mammals, as well as all major disease areas, including neurological disorders, cancer and infectious diseases. Addressing the needs of the pharmaceutical industry, this unique handbook adopts a broad perspective on the use of animals in the early part of the drug development process, including regulatory rules and limitations, as well as numerous examples from real-life drug development projects. After a general introduction to the topic, the expert contributors from research-driven pharmaceutical companies discuss the basic considerations of using animal models, including ethical issues. The main part of the book systematically surveys the most important disease areas for current drug development, from cardiovascular to endocrine disorders, and from infectious to neurological diseases. For each area, the availability of animal models for target validation, hit finding and lead profiling is reviewed, backed by numerous examples of both successes and failures among the use of animal models. The whole is rounded off with a discussion of perspectives and challenges. Key knowledge for drug researchers in industry as well as academia.

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Christine Lee A. Inherited Bleeding Disorders in Women


The essential guide for understanding and treating women with inherited bleeding disorders, revised and updated Now in its second edition, Inherited Bleeding Disorders in Women includes the most recent developments and research in the field. This important guide offers the most current information available for the effective management of these complex and difficult to diagnose disorders. Treating women with inherited bleeding disorders can be challenging and requires close collaboration among practitioners in different specialties. This important guide is written by a team of international experts who offer advice and practical suggestions for treating women with inherited bleeding disorders. Inherited Bleeding Disorders in Women comprehensively covers obstetric and gynecological issues for carriers of hemophilia, women with von Willebrand disease, rare bleeding disorders and inherited platelet disorders. This important resource: Offers an updated guide for hematologists, obstetricans and gynecologists and other clinicians treating women with inherited bleeding disorders Includes information for treating both common and rare bleeding disorders Contains the most recent developments and advances in the field for the treatment and management of inherited bleeding disorders in women Presents information from noted experts in the field Offers a multidisciplinary approach to the topic Written for hematologists, obstetricians and gynecologists and other clinicians working with women, Inherited Bleeding Disorders in Women has been fully revised and updated and continues to serve as a trusted guide for the management and treatment of women with inherited bleeding disorders.

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Fabrizio Bogliatto A Practical Guide to Vulval Disease. Diagnosis and Management


This book is a practical guide to the diagnosis and management of vulval disorders. It offers guidance for all those who are treating patients with vulval disease at trainee and specialist level, helping to improve management for the patient and prevent delays in diagnosis, including referrals to specialists. It contains key information about diagnosis, investigation and basic management, with a section on signs and symptoms guides the reader to the correct chapter for the treatment of that disease. The experienced authors include updated classification and terminology of vulval disease with an explanation of how this should be useful in clinical practice and guidance as to when the patient should be referred on to a specialist. As vulval diseases are different to those of the rest of the skin patients with vulval disease present a large unmet need, often with delays in diagnosis due to a lack of training from physicians. This practical guide provides the specialist knowledge required for diagnosis and treatment of these conditions.

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Malcolm Macleod Neurology. Clinical Cases Uncovered


Neurology is a rapidly advancing core topic within the clinical curriculum and students and junior doctors are expected to recognise, understand and know how to investigate and manage many neurological-related disorders and conditions. Neurology: Clinical Cases Uncovered leads students through the clinical approach to managing neurological problems via real-life patient cases and outcomes. Following a question-answer approach to developing the narrative, and including self-assessment MCQs, EMQs and SAQs, the book includes 27 fully-illustrated cases covering a wide range of neurological presentations and conditions. Ideal for medical students with clinical attachments in neurology, and in the run up to examinations, the book will also be useful to doctors in training in general internal medicine, medicine of the elderly, psychiatry and neurology.

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Concettina Tolomeo Nursing Care in Pediatric Respiratory Disease


Pediatric respiratory disorders are responsible for a number of acute and chronic health conditions and are a leading cause of pediatric emergency room visits and hospitalizations. More than ever, nurses and nurse practitioners must have an understanding of the anatomy, pathophysiology, diagnosis and state of the art treatments in pediatric respiratory disease as they are often the first to come in contact with and recognize respiratory problems in children. Nursing Care in Pediatric Respiratory Disease seeks to provide both nurses and nurse practitioners with this information in order to aid them in the diagnosis and treatment of children suffering from acute and chronic respiratory disorders. Nursing Care in Pediatric Respiratory Disease opens with an overview of the anatomy and physiology of the respiratory system, best practices for assessing respiratory symptoms in children, and common respiratory therapies and treatment methods. It then proceeds through an examination of varying acute and chronic upper and lower respiratory diseases spanning from asthma and cystic fibrosis to vocal cord paralysis and sinusitis in both hospital and ambulatory settings. Nursing Care in Pediatric Respiratory Disease provides nurses and other health care providers with a comprehensive and practical resource which allows them to collaborate and advocate more effectively, as well as educate both the family and child in management of respiratory disorders.

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Livia Candelise Evidence-Based Neurology. Management of Neurological Disorders


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Paul Reading ABC of Sleep Medicine


A practical illustrated guide to sleep disorders which will give health professionals confidence in this complex area of diagnosis and management. It explains the differences between normal and abnormal sleep, and looks in depth at individual disorders such as sleep apnoea, insomnia, narcolepsy, restless legs syndrome and the parasomnias, as well as sleep disorders as a comorbidity of neurodegenerative and psychiatric disease. Common sleep disorders in children are addressed in detail before concluding with an overview of pharmacological treatments and how commonly used drugs might affect sleep.

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Margareta Blombäck Essential Guide to Blood Coagulation


A practical guide to laboratory diagnosis and treatment of hemostatic disorders. This concise book distils the most clinically up-to-date information on thrombotic and bleeding disorders, including the latest treatment strategies, for key conditions and diseases. Essential Guide to Blood Coagulation covers both the stable and the acute stages of hereditary and acquired bleeding and thrombotic disorders. Faced with a bleeding patient, it may be difficult to determine whether blood loss is due to a local factor, or an underlying hemostatic defect. There are a range of laboratory tests which can be performed to identify the cause of bleeding in a patient. This book highlights the tests that can be used in the laboratory to aid diagnosis. Essential Guide to Blood Coagulation has been updated to include the new anticoagulants and now has a dedicated chapter on antiplatelet drugs. This invaluable guide will help all those treating patients to expand their knowledge of hemostatic disorders. TITLES OF RELATED INTEREST Hemophilia and Hemostasis: A Case-Based Approach to Management Second Edition Alice Ma, Harold Roberts, Miguel Escobar ISBN: 978-0-470-65976-2 Quality in Laboratory Hemostasis and Thrombosis Second Edition Steve Kitchen, John Olson, Eric Preston (due May 2013) ISBN: 978-0-470-67119-1

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Nasim Akhtar ABC of Arterial and Venous Disease


ABC of Arterial and Venous Disease provides a structured, practical approach to clinical assessment, investigation and management of the most commonly presenting arterial and venous disorders. Structural and functional abnormalities of arteries and veins manifest clinically in a broad spectrum of disorders, including cerebrovascular and carotid artery disease, abdominal aortic aneurysms, acute and chronic limb ischaemia, vasculitis and varicose veins. This revised edition incorporates new chapters on coronary artery disease and acute coronary syndrome, visceral artery stenosis and mesenteric ischaemia, and arteriovenous malformations. Many of these common or chronic conditions first present for initial assessment by primary health care professionals. Case vignettes have been added to relevant chapters to aid understanding and decision making. Fully up to date and from an expert editor and contributor team, ABC of Arterial and Venous Disease remains a useful resource for non-specialist doctors such as general practitioners, family physicians and junior doctors in training. It is also a relevant guide for all other primary health care professionals working within the multidisciplinary teams responsible for patients with chronic arterial and venous disorders.

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Norman Sartorius Depression and Heart Disease


Recently, there has been a growing awareness of the multiple interrelationships between depression and various physical diseases. Patients with psychiatric problems, particularly depression, may be more susceptible to cardiovascular disorders. Depression and Heart Disease synthesizes current evidence, including some previously unpublished data, in a concise, easy-to-read format. The authors succinctly describe the epidemiology, pathogenesis (including cytokines and genetics), and risk factors of the comorbidity between depression and heart disease. The book also reviews the best pharmacological and psychotherapeutic approaches for people with this comorbidity.

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Aron Gottesman Understanding Systemic Risk in Global Financial Markets


An accessible and detailed overview of the risks posed by financial institutions Understanding Systemic Risk in Global Financial Markets offers an accessible yet detailed overview of the risks to financial stability posed by financial institutions designated as systemically important. The types of firms covered are primarily systemically important banks, non-banks, and financial market utilities such as central counterparties. Written by Aron Gottesman and Michael Leibrock, experts on the topic of systemic risk, this vital resource puts the spotlight on coherency, practitioner relevance, conceptual explanations, and practical exposition. Step by step, the authors explore the specific regulations enacted before and after the credit crisis of 2007-2009 to promote financial stability. The text also examines the criteria used by financial regulators to designate firms as systemically important. The quantitative and qualitative methods to measure the ongoing risks posed by systemically important financial institutions are surveyed. A review of the regulations that identify systemically important financial institutions The tools to use to detect early warning indications of default A review of historical systemic events their common causes Techniques to measure interconnectedness Approaches for ranking the order the institutions which pose the greatest degree of default risk to the industry Understanding Systemic Risk in Global Financial Markets offers a must-have guide to the fundamentals of systemic risk and the key critical policies that work to reduce systemic risk and promoting financial stability.

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B. A. Kazakovtsev Mental Disorders in Epilepsy


The monograph shows the opportunity to study the pathogenesis of mental disorders in epilepsy based on the characteristics of its fl ow using clinical methods, structural dynamic, epidemiological and statistical analysis. Structural and dynamic analysis of the major clinical manifestations of the disease (features of personality changes, paroxysmal disorders, psychotic symptoms, dementia) held in accordance with the main patterns of development of the disease, its types and stages. On the basis of the multi-axial classifi cation of epilepsy was developed a model that allows in a retrospective analysis of an-amnestic data and clinical assessment to establish clinical and social criteria for prognosis prediction.

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Andres Pinto Risk Assessment and Oral Diagnostics in Clinical Dentistry


Many diseases can have an impact upon oral health and/or the safe delivery of dental care. Consequently, oral health care providers need to be comfortable with assessing the risk of providing dental care to their patients with systemic disease as well as the evaluation of oral conditions that may represent manifestations or consequences of systemic disease. Risk Assessment and Oral Diagnostics in Clinical Dentistry aims to enable the dental practitioner to comfortably and capably assess when medical conditions may impact dental care and diagnose oral conditions using routine testing modalities. This clinical guide contains succinct and detailed text with visual aids regarding how to obtain and perform diagnostic tests, how to interpret these tests, and the implications of tests results upon the management of medically complex dental patients and patients with oral conditions. Color photographs show conditions, testing equipment, and test results. An appendix highlights the ten most common oral medicine disorders encountered in dental practice.

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Parag Kulkarni Reinforcement and Systemic Machine Learning for Decision Making


Reinforcement and Systemic Machine Learning for Decision Making There are always difficulties in making machines that learn from experience. Complete information is not always available—or it becomes available in bits and pieces over a period of time. With respect to systemic learning, there is a need to understand the impact of decisions and actions on a system over that period of time. This book takes a holistic approach to addressing that need and presents a new paradigm—creating new learning applications and, ultimately, more intelligent machines. The first book of its kind in this new and growing field, Reinforcement and Systemic Machine Learning for Decision Making focuses on the specialized research area of machine learning and systemic machine learning. It addresses reinforcement learning and its applications, incremental machine learning, repetitive failure-correction mechanisms, and multiperspective decision making. Chapters include: Introduction to Reinforcement and Systemic Machine Learning Fundamentals of Whole-System, Systemic, and Multiperspective Machine Learning Systemic Machine Learning and Model Inference and Information Integration Adaptive Learning Incremental Learning and Knowledge Representation Knowledge Augmentation: A Machine Learning Perspective Building a Learning System With the potential of this paradigm to become one of the more utilized in its field, professionals in the area of machine and systemic learning will find this book to be a valuable resource.

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Lionel Ginsberg Lecture Notes: Neurology


Now in two colours throughout, this new edition of Lecture Notes: Neurology contains the core neurological information required, whichever branch of clinical medicine you choose. Reflecting current clinical practice, the latest advances in the diagnosis and management of neurological diseases are concisely covered. The book is divided into two parts. The Neurological Approach looks at neurological history taking. The neurological examination is then discussed in detail – consciousness, cognitive function, vision and other cranial nerves, motor function, sensation and autonomic function. In part two, Neurological Disorders, the common neurological conditions are described, along with neurological emergencies and neuro-rehabilitation. Featuring a self-assessment section, and with clinical scenario and key points boxes throughout, Lecture Notes: Neurology is ideal for medical students, junior doctors, and specialist nurses who want a concise introduction to clinical neurology that can be used as a core text or as a revision resource.

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John Boardman Systemic Thinking. Building Maps for Worlds of Systems


Systemic thinking is the process of understanding how systems influence one another within a world of systems and has been defined as an approach to problem solving by viewing «problems» as parts of an overall system, rather than reacting to a specific part, outcome, or event. This book provides a complete overview of systemic thinking, exploring a framework and graphical technique for understanding and identifying new ways to more efficiently solve problems and create solutions. Demystifying the conjunction of systems concepts and systemic diagramming techniques, this comprehensive pocket guide introduces and explains the basis of systemigrams, how to create a systemigram and a SystemiShow, illuminates multiple complex problems, and provides an overview of what purpose they serve for todays industry professionals. Systemic Thinking: Building Maps for Worlds of Systems: Includes illustrative systemigrams and case studies Includes the SystemiTool software, developed by the authors Provides an overview of systemic thinking, particularly with regard to systemigrams Incorporates graphical representations of systemigrams Instructs how and when to implement a systemigram when a problem arises An invaluable book for industry professionals—specifically, technical leaders in industry and business trying to confront complex problems—Systemic Thinking is also ideal for postgraduate students in engineering and business management.

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Tullio Scrimali Neuroscience-based Cognitive Therapy. New Methods for Assessment, Treatment and Self-Regulation


A pioneer of CBT explores recent advances in neuroscience, showing how they can be applied in practice to improve the effectiveness of cognitive therapy for clients with a wide range of diagnoses including mood disorders, anxiety disorders, eating disorders and schizophrenia Utilizes the latest advances in neuroscience to introduce tools that allow clinicians, for the first time, to directly ‘measure the effectiveness of cognitive therapy interventions Rigorously based in neuroscientific research, yet designed to be readable and jargon-free for a professional market of CBT practitioners Covers theory, assessment, and the treatment of a wide range of specific disorders including anxiety disorders, mood disorders, eating disorders, addictions and schizophrenia Written by a respected pioneer in the field

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Elias Hanna B. Practical Cardiovascular Medicine


Prepare yourself for success with this unique cardiology primer which distils the core information you require and presents it in an easily digestible format. Provides cardiologists with a thorough and up-to-date review of cardiology, from pathophysiology to practical, evidence-based management Ably synthesizes pathophysiology fundamentals and evidence based approaches to prepare a physician for a subspecialty career in cardiology Clinical chapters cover coronary artery disease, heart failure, arrhythmias, valvular disorders, pericardial disorders, and peripheral arterial disease Practical chapters address ECG, coronary angiography, catheterization techniques, ecnocardiography, hemodynamics, and electrophysiological testing Includes over 650 figures, key notes boxes, references for further study, and coverage of clinical trials Review questions at the end of each chapter help clarify topics and can be used for Board preparation – over 375 questions in all!

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Curtis Dewey W. Practical Guide to Canine and Feline Neurology


Now in full color, Practical Guide to Canine and Feline Neurology, Third Edition provides a fully updated new edition of the most complete resource on managing neurology cases in small animal practice, with video clips on a companion website.•Provides comprehensive information for diagnosing and treating neurological conditions•Printed in full color for the first time, with 400 new or improved images throughout•Offers new chapters on differential diagnosis, magnetic resonance imaging, and movement disorders•Retains the logical structure and easy-to-follow outline format of the previous editions •Includes access to video clips of specific disorders and a how-to video demonstrating the neurologic assessment online and a link to a digital canine brain atlas at www.wiley.com/go/dewey/neurologyNow in full color, Practical Guide to Canine and Feline Neurology, Third Edition provides a fully updated new edition of the most complete resource on managing neurology cases in small animal practice, with video clips on a companion website. •Provides comprehensive information for diagnosing and treating neurological conditions •Printed in full color for the first time, with 400 new or improved images throughout •Offers new chapters on differential diagnosis, magnetic resonance imaging, and movement disorders •Retains the logical structure and easy-to-follow outline format of the previous editions •Includes access to video clips of specific disorders and a how-to video demonstrating the neurologic assessment online and a link to a digital canine brain atlas at www.wiley.com/go/dewey/neurology

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Antovic Jovan P. Essential Guide to Blood Coagulation


A practical guide to laboratory diagnosis and treatment of hemostatic disorders. This concise book covers all you need to know to manage thrombotic and bleeding disorders, distilling the most clinically up-to-date information, and including the latest treatment strategies for key conditions and diseases. Essential Guide to Blood Coagulation covers both the stable and the acute stages of hereditary and acquired bleeding and thrombotic disorders. Faced with a bleeding patient, it may be difficult to determine whether blood loss is due to a local factor or an underlying hemostatic defect. There are a range of laboratory tests which can be performed to identify the cause of bleeding in a patient. This book highlights the tests that can be used in the laboratory to aid diagnosis. Originally published in Swedish, Essential Guide to Blood Coagulation, has been revised to include the latest treatment strategies available for patients and will help clinicians to expand their knowledge of hemostatic disorders.

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